Cytochrome C Oxidase Subunit 6A1 (COX6A1) Antibody Pair

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988€ (5 × 96 tests)

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935106861
info@markelab.com
name
Cytochrome C Oxidase Subunit 6A1 (COX6A1) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx117358
tested applications
ELISA

Description

COX6A1 Antibody Pair for use in Sandwich ELISA assay development.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Antibody Pairs
Immunogen Target
Cytochrome C Oxidase Subunit 6A1 (COX6A1)
Host
Capture Host: Rabbit
Detection Host: Rabbit
Reactivity
Human, Rat, Mouse, Guinea pig, Pig, Dog
Assay Data
Sandwich
Assay Type
Sandwich
Clonality
Capture Clonality: Polyclonal
Detection Clonality: Polyclonal
Conjugation
Biotin
Isotype
Capture Isotype: IgG
Detection Isotype: IgG
Size 1
5 × 96 tests
Form
Liquid
Tested Applications
ELISA
Buffer
0.01 M PBS, pH 7.4, 50% glycerol.
Availability
Shipped within 5-10 working days.
Dry Ice
No
Background
Antibody pair for COX6A1
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Descripción

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Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented.

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COX6A1 Antibody is a Rabbit Polyclonal antibody against COX6A1. Cytochrome c oxidase (COX), the terminal enzyme of the mitochondrial respiratory chain, catalyzes the electron transfer from reduced cytochrome c to oxygen. It is a heteromeric complex consisting of 3 catalytic subunits encoded by mitochondrial genes and multiple structural subunits encoded by nuclear genes. The mitochondrially-encoded subunits function in the electron transfer and the nuclear-encoded subunits may function in the regulation and assembly of the complex. This nuclear gene encodes polypeptide 1 (liver isoform) of subunit VIa, and polypeptide 1 is found in all non-muscle tissues. Polypeptide 2 (heart/muscle isoform) of subunit VIa is encoded by a different gene, and is present only in striated muscles. These two polypeptides share 66% amino acid sequence identity. It has been reported that there may be several pseudogenes on chromosomes 1, 6, 7q21, 7q31-32 and 12. However, only one pseudogene (COX6A1P) on chromosome 1p31.1 has been documented.

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