Cyclic AMP-Dependent Transcription Factor ATF-3 (ATF3) Antibody
292.5€ (80 µl)
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935106861
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name
Cyclic AMP-Dependent Transcription Factor ATF-3 (ATF3) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx028913
tested applications
ELISA, WB, FCM
Description
Cyclic AMP-Dependent Transcription Factor ATF-3 is a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. Multiple transcript variants encoding two different isoforms have been found for this gene. The longer isoform represses rather than activates transcription from promoters with ATF binding elements. The shorter isoform (deltaZip2) lacks the leucine zipper protein-dimerization motif and does not bind to DNA, and it stimulates transcription presumably by sequestering inhibitory co-factors away from the promoter. It is possible that alternative splicing of the ATF3 gene may be physiologically important in the regulation of target genes.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cyclic AMP-Dependent Transcription Factor ATF-3 (ATF3) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, FCM: 1/10 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified through a protein A column, followed by peptide affinity purification. |
| Size 1 | 80 µl |
| Size 2 | 400 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, FCM |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P18847 |
| Gene ID | 467 |
| NCBI Accession | NP_001025458.1, NM_001030287.3 |
| OMIM | 603148 |
| Alias | ATF3,ATF-3 |
| Background | Antibody anti-ATF3 |
| Status | RUO |
Descripción
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Cyclic AMP-Dependent Transcription Factor ATF-3 (ATF3) Antibody
ATF3 Antibody is a Rabbit Polyclonal antibody against ATF3. This gene encodes a member of the mammalian activation transcription factor/cAMP responsive element-binding (CREB) protein family of transcription factors. This gene is induced by a variety of signals, including many of those encountered by cancer cells, and is involved in the complex process of cellular stress response. Multiple transcript variants encoding different isoforms have been found for this gene. It is possible that alternative splicing of this gene may be physiologically important in the regulation of target genes.
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