Cyclic ADP Ribose Hydrolase (CD38) Antibody (PE)
520€ (100 µg)
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935106861
info@markelab.com
name
Cyclic ADP Ribose Hydrolase (CD38) Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx413123
tested applications
FCM
Description
Cyclic ADP Ribose Hydrolase (CD38) Antibody (PE) is a Rat Monoclonal antibody against Cyclic ADP Ribose Hydrolase (CD38).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cyclic ADP Ribose Hydrolase (CD38) |
| Host | Rat |
| Reactivity | Mouse |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG2a |
| Purification | Purified |
| Size 1 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | PBS, 0.5% BSA. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. |
| Dry Ice | No |
| UniProt ID | P56528 |
| Alias | ADPRC1,Cadpr1,ADPRC 1,ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1,2'-phospho-ADP-ribosyl cyclase,2'-phospho-cyclic-ADP-ribose transferase,ADP-ribosyl cyclase 1,Cyclic ADP-ribose hydrolase 1 |
| Background | Antibody anti-CD38 |
| Status | RUO |
Descripción
CD38 is a multifunctional membrane glycoprotein expressed on a variety of cells, including immune cells (B cells, T cells, monocytes, and natural killer cells), as well as non-hematopoietic cells like those in the pancreas, brain, and muscle. Initially identified as a cell-surface receptor on lymphocytes, CD38 has since been recognized for its roles in enzyme-mediated metabolism, cell adhesion, and signal transduction. This protein is particularly well-known for its enzymatic activity in catalyzing the synthesis and hydrolysis of cyclic ADP-ribose (cADPR) from NAD+, which serves as an important second messenger in calcium signaling pathways. CD38 plays crucial roles in the regulation of intracellular calcium levels, influencing processes such as cell activation, proliferation, and differentiation.
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