CXADR-Like Membrane Protein (CLMP) Antibody

Este producto es parte de CLMP - CXADR like membrane protein
CXADR-Like Membrane Protein (CLMP) Antibody

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935106861

info@markelab.com

Precio

387.5€ (200 µl)

Antibody anti-CLMP

proveedor

Abbexa

reference

abx432515

Tested Applications

P-ELISA, WB

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

CLMP Antibody is a Goat Polyclonal antibody against CLMP.


Background

CLMP is a transmembrane protein belonging to the immunoglobulin superfamily and shares structural similarity with the coxsackie and adenovirus receptor (CXADR). CLMP is widely expressed in epithelial and endothelial tissues, where it contributes to tight junction formation and maintenance of cell polarity. It mediates homophilic adhesion and strengthens intercellular junctions, playing a role in epithelial barrier integrity. Mutations in CLMP have been linked to congenital short bowel syndrome, a rare developmental disorder characterized by reduced intestinal length due to impaired embryonic gut elongation. CLMP is thought to regulate cellular signaling pathways that influence proliferation and differentiation during organogenesis. In addition to its developmental roles, CLMP has been implicated in regulating vascular permeability and may contribute to immune cell trafficking in inflammatory conditions. Structurally, CLMP contains extracellular immunoglobulin-like domains that mediate adhesion and intracellular domains that interact with cytoskeletal proteins to stabilize cell-cell junctions. Dysregulation of CLMP expression has been observed in certain cancers, suggesting a potential role in tumor progression and metastasis. Current research focuses on understanding its signaling mechanisms and exploring its therapeutic potential in tissue repair and developmental disorders.

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

CXADR-Like Membrane Protein (CLMP)


host

Goat


conjugation

Unconjugated


form

Liquid


tested applications

P-ELISA, WB


purification

Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.


buffer

Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.


size 1

200 µl


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

CLMP


dry ice

No


availability

Shipped within 1-3 working days.


alias

ACAM,ASAM,CSBM,CSBS,Adipocyte adhesion molecule,Coxsackie- and adenovirus receptor-like membrane protein,CAR-like membrane protein


NCBI accession

NP_079045.1


note

This product is for research use only.


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