Crystallin Alpha A (CRYAA) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Crystallin Alpha A (CRYAA) Antibody is a Mouse Monoclonal antibody against Crystallin Alpha A (CRYAA).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Crystallin Alpha A (CRYAA) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Size 1 | 5 µg |
| Size 2 | 20 µg |
| Size 3 | 100 µg |
| Availability | Shipped within 5-10 working days. |
| Dry Ice | No |
| Background | Antibody anti-CRYAA |
| Status | RUO |
Descripción
Related Products
Human CRYAA(Alpha-crystallin A chain) ELISA Kit
Ver Producto
Recombinant Human CRYAA
Ver Producto
Alpha-Crystallin A Chain (CRYAA) Antibody
CRYAA Antibody is a Rabbit Polyclonal antibody against CRYAA. Mammalian lens crystallins are divided into alpha, beta, and gamma families. Alpha crystallins are composed of two gene products: alpha-A and alpha-B, for acidic and basic, respectively. Alpha crystallins can be induced by heat shock and are members of the small heat shock protein (HSP20) family. They act as molecular chaperones although they do not renature proteins and release them in the fashion of a true chaperone; instead they hold them in large soluble aggregates. Post-translational modifications decrease the ability to chaperone. These heterogeneous aggregates consist of 30-40 subunits; the alpha-A and alpha-B subunits have a 3:1 ratio, respectively. Two additional functions of alpha crystallins are an autokinase activity and participation in the intracellular architecture. The encoded protein has been identified as a moonlighting protein based on its ability to perform mechanistically distinct functions. Alpha-A and alpha-B gene products are differentially expressed; alpha-A is preferentially restricted to the lens and alpha-B is expressed widely in many tissues and organs. Defects in this gene cause autosomal dominant congenital cataract (ADCC).
Ver Producto