Coxsackievirus And Adenovirus Receptor (CXADR) Antibody
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Description
Coxsackievirus And Adenovirus Receptor (CXADR) Antibody is a Rabbit polyclonal antibody for the detection of Human Coxsackievirus And Adenovirus Receptor (CXADR).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Coxsackievirus And Adenovirus Receptor (CXADR) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P78310 |
| Gene ID | 1525 |
| NCBI Accession | NP_001193992.1 |
| Background | Antibody anti-CXADR |
| Status | RUO |
Descripción
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Human CXADR (Coxsackievirus and adenovirus receptor) ELISA Kit
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CXADR antibody
Component of the epithelial apical junction complex that may function as a homophilic cell adhesion molecule and is essential for tight junction integrity. Also involved in transepithelial migration of leukocytes through adhesive interactions with JAML a transmembrane protein of the plasma membrane of leukocytes. The interaction between both receptors also mediates the activation of gamma-delta T-cells, a subpopulation of T-cells residing in epithelia and involved in tissue homeostasis and repair. Upon epithelial CXADR-binding, JAML induces downstream cell signaling events in gamma-delta T-cells through PI3-kinase and MAP kinases. It results in proliferation and production of cytokines and growth factors by T-cells that in turn stimulate epithelial tissues repair. (Microbial infection) Acts as a receptor for adenovirus type C(PubMed:9733828, PubMed:10666333, PubMed:12297051, PubMed:10567268). Acts as a receptor for Coxsackievirus B1 to B6(PubMed:14978041, PubMed:10814575).
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