Cow Vascular Endothelial Growth Factor C (VEGFC) Protein
455€ (50 µg)
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935106861
info@markelab.com
name
Cow Vascular Endothelial Growth Factor C (VEGFC) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx166317
tested applications
WB, SDS-PAGE
Description
VEGFC Protein is a recombinant Cow protein expressed in E. coli.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Vascular Endothelial Growth Factor C (VEGFC) |
| Host | E. coli |
| Origin | Cow |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 16.8 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Ala113-Arg228 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 90% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 500 µg |
| Size 5 | 1 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-7 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | VRP,Flt4-L,LMPH1D,LMPHM4,Vascular endothelial growth factor-related protein |
| Background | Protein VEGFC |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
VEGFC is primarily responsible for lymphangiogenesis, the formation of lymphatic vessels, by binding to VEGFR-3 on lymphatic endothelial cells During embryonic development and tissue repair, VEGFC promotes the sprouting and maturation of lymphatic vessels VEGFC also activates VEGFR-2 in certain contexts, contributing to angiogenesis and vascular remodeling VEGFC plays a significant role in pathological processes, including cancer metastasis, where it enhances lymphatic vessel growth and facilitates tumor cell dissemination via the lymphatic system Overexpression of VEGFC is observed in various cancers such as breast cancer, melanoma, and prostate cancer, correlating with lymph node metastasis Targeting VEGFC signaling is a promising strategy to inhibit lymphangiogenesis and reduce cancer spread while maintaining tissue fluid balance and immune cell trafficking
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