Cow Protein Argonaute-2 (AGO2) ELISA Kit

Este producto es parte de AGO - Protein Argonaute
Cow Protein Argonaute-2 (AGO2) ELISA Kit

Pida mas información

935106861

info@markelab.com

Precio

715€ (96 tests)

Elisa kits for AGO2

proveedor

Abbexa

reference

abx515446

Tested Applications

ELISA

reactivity

Cow

status

RUO

clonality

Descripción

Cow Protein Argonaute-2 (AGO2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Cow Protein argonaute-2 concentrations in tissue homogenates, cell lysates and other biological fluids.


Background

AGO2 is the most well-characterized and catalytically active member of the Argonaute family, playing a central role in the RISC complex. AGO2 binds miRNAs and small interfering RNAs (siRNAs) to mediate both translational repression and endonucleolytic cleavage (slicing) of target mRNAs. Its conserved PIWI domain is responsible for its slicer activity, enabling AGO2 to degrade complementary mRNA targets directly. AGO2 is highly expressed in many tissues and is involved in crucial cellular processes, including gene silencing, developmental regulation, and the cellular response to viral infections. Dysregulation of AGO2 contributes to various pathological conditions, including cancers, neurodegenerative diseases, and immune disorders, due to its impact on gene expression and miRNA/siRNA pathways. AGO2 is also being explored as a potential therapeutic target in RNA-based therapies.

Características del producto

category

ELISA Kits


immunogen target

Protein Argonaute-2 (AGO2)


reactivity

Cow


test range

15.6 pg/ml - 1000 pg/ml


assay data

Quantitative


form

Lyophilized


detection method

Colorimetric


sample type

Tissue homogenates, cell lysates and other biological fluids.


size 1

96 tests


alias

CASC7,EIF2C2,LESKRES,LINC00980,PPD,Q10


storage

Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.


or code

AGO2


dry ice

No


note

This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.


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