Cow Integrin Beta 2 (ITGB2) ELISA Kit
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935106861
info@markelab.com
Precio
715€ (96 tests)
Elisa kits for ITGB2
proveedor
Abbexareference
abx512305Tested Applications
ELISAreactivity
Cowstatus
RUOclonality
Descripción
Cow Integrin Beta 2 (ITGB2) ELISA Kit is an ELISA Kit for the in vitro quantitative measurement of Cow Integrin Beta 2 (ITGB2) concentrations in tissue homogenates, cell lysates and other biological fluids.
Background
ITGB2, or integrin subunit beta 2, is a protein that plays a central role in leukocyte adhesion and signaling, facilitating the immune system's response to infections and inflammation. ITGB2, also known as CD18, is part of the integrin family, which consists of transmembrane receptors involved in cell-cell and cell-extracellular matrix (ECM) interactions. Integrins are heterodimeric proteins formed by the association of alpha (α) and beta (β) subunits. In particular, ITGB2 pairs with various alpha integrin subunits to form key receptors known as beta-2 integrins. Beta-2 integrins are primarily expressed on leukocytes (white blood cells) and are essential for mediating cell adhesion, migration, phagocytosis, and immune surveillance. The four major integrins that involve ITGB2 are LFA-1 (αLβ2, CD11a/CD18), Mac-1 (αMβ2, CD11b/CD18), gp150/95 (αXβ2, CD11c/CD18), and αDβ2 (CD11d/CD18). These integrins are vital for the immune system's ability to respond to infections and regulate inflammation.
Características del producto
category
ELISA Kits
immunogen target
Integrin Beta 2 (ITGB2)
reactivity
Cow
test range
0.625 ng/ml - 40 ng/ml
sensitivity
< 0.29 ng/ml
assay type
Sandwich
assay data
Quantitative
form
Lyophilized
detection method
Colorimetric
sample type
Tissue homogenates, cell lysates and other biological fluids.
size 1
96 tests
alias
LAD,CD18,MF17,MFI7,LCAMB,LFA-1,MAC-1,Integrin beta-2,Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta,Complement receptor C3 subunit beta
storage
Shipped at 4 °C. Upon receipt, store the kit according to the storage instruction in the kit's manual.
or code
ITGB2
dry ice
No
uniprot id
note
This product is for research use only. The range and sensitivity is subject to change. Please contact us for the latest product information. For accurate results, sample concentrations must be diluted to mid-range of the kit. If you require a specific range, please contact us in advance or write your request in your order comments. Please note that our ELISA and CLIA kits are optimised for detection of native samples, rather than recombinant proteins. We are unable to guarantee detection of recombinant proteins, as they may have different sequences or tertiary structures to the native protein.
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