Corticosteroid Binding Globulin (SERPINA6) Antibody
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Description
SERPINA6 Antibody is a Rabbit Polyclonal antibody against SERPINA6. This gene encodes an alpha-globulin protein with corticosteroid-binding properties. This is the major transport protein for glucorticoids and progestins in the blood of most vertebrates. The gene localizes to a chromosomal region containing several closely related serine protease inhibitors which may have evolved by duplication events.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Corticosteroid Binding Globulin (SERPINA6) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | ELISA: 1 µg/ml, WB: 1/500 - 1/2000. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified by affinity chromatography. |
| Size 1 | 20 µl |
| Size 2 | 100 µl |
| Size 3 | 2 × 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB |
| Buffer | PBS, pH 7.3, containing 0.02% sodium azide, 50% glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P08185 |
| Gene ID | 866 |
| NCBI Accession | NP_001747.2 |
| Alias | CBG,Corticosteroid-binding globulin,Serpin A6,Transcortin |
| Background | Antibody anti-SERPINA6 |
| Status | RUO |
| Note | Concentration: > 0.2 mg/ml - |
Descripción
SERPINA6, also known as Corticosteroid-Binding Globulin (CBG), is a significant member of the serpin (serine protease inhibitor) superfamily, which plays a vital role in various biological processes, particularly in the regulation of glucocorticoids like cortisol. Glucocorticoids are essential for numerous physiological processes, including metabolism, immune response, and stress adaptation. SERPINA6 is primarily responsible for binding and transporting glucocorticoids in the blood, ensuring that these hormones are available in a regulated manner for physiological needs.
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