Complement Decay-Accelerating Factor (CD55) Antibody (PE)
429€ (100 tests)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Complement Decay-Accelerating Factor (CD55) Antibody (PE)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx139390
Tested Applications
FCM
Description
CD55 Antibody is a Mouse Monoclonal against CD55.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Complement Decay-Accelerating Factor (CD55) Immunogen: HPB-ALL Human T cell line. |
| Host | Mouse |
| Reactivity | Human, Monkey |
| Detection Method | Laser Line: 550 Excitation/Emission: 565/575 |
| Recommended Dilution | FCM: 10 µl/100 µl of whole blood or 106 cells. Validated in IHC-P. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgM |
| Clone ID | C571 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing TBS solution with 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P08174 |
| Gene ID | 1604 |
| Alias | Cromer blood group,CR,TC,DAF,CROM,CHAPLE,Complement decay-accelerating factor |
| Background | Antibody anti-CD55 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD55, also known as decay-accelerating factor (DAF), is a glycoprotein that plays a critical role in regulating the complement system, a part of the innate immune response. The primary function of CD55 is to protect host cells from complement-mediated damage by inhibiting the formation of C3 and C5 convertases, key enzymes in the complement activation pathways. CD55 is widely expressed on the surface of many cell types, including erythrocytes, leukocytes, endothelial cells, and epithelial cells. Its expression is essential for preventing unintended complement activation on host tissues, which could lead to cell lysis and tissue damage. CD55 is particularly important in safeguarding cells from the alternative pathway and classical pathway of complement activation. The complement system is a major defense mechanism that helps the body clear pathogens through opsonization, inflammation, and lysis of infected or foreign cells. By regulating this system, CD55 ensures that the complement system does not damage self-cells, thus maintaining tissue integrity during immune responses.
Productos relacionados
Complement Decay-Accelerating Factor (CD55) Antibody
CD55 Antibody is a Rabbit Polyclonal antibody against CD55. This gene encodes a protein involved in the regulation of th…
Ver producto
Complement Decay-Accelerating Factor (CD55) Antibody
Rabbit polyclonal antibody against CD55 protein. Immunogen region is Internal.…
Ver producto
Complement Decay-Accelerating Factor (CD55) Antibody
This gene encodes a protein involved in the regulation of the complement cascade. The encoded glycoprotein is also known…
Ver producto