Complement Component 3a (C3a) Antibody Pair

Este producto es parte de Complement C3
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1495€ (5 × 96 tests)

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935106861
info@markelab.com
name
Complement Component 3a (C3a) Antibody Pair
category
Antibody Pairs
provider
Abbexa
reference
abx370410
tested applications
ELISA

Description

Complement Component 3a (C3a) Antibody Pair for use in Sandwich ELISA assay development. 

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Antibody Pairs
Immunogen Target
Complement Component 3a (C3a)
Reactivity
Rat
Assay Data
Capture: Rabbit  Polyclonal
Detection:  Rabbit  Polyclonal (Biotin)
Assay Type
Sandwich
Test Range
6.25 pg/ml - 400 pg/ml
Recommended Dilution
Dilute the Capture Antibody 125-fold with Coating Buffer.  Dilute the Biotin-Conjugated Detection Antibody 200-fold with Detection Antibody Diluent.  Optimal dilutions/concentrations should be determined by the end user.
Size 1
5 × 96 tests
Size 2
10 × 96 tests
Form
Standard: Lyophilized--Liquid (Capture Antibody and Detection Antibody)
Reconstitute the standard with Standard Diluent. The volume, and therefore standard concentration, should be determined by the end user.
Tested Applications
ELISA
Buffer
The Capture and Detection Antibody both contain 0.1% sodium azide.
Availability
Shipped within 5-20 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
ASP,C3a,C3b,AHUS5,ARMD9,CPAMD1,HEL-S-62p,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
Background
Antibody Pair for C3
Status
RUO
Note
This antibody pair contains ( 5 x 96 det):    Detection:  50 µg  Capture:  200 µg  Standard:  1 µg
This product is for research use only.

Descripción

Complement C3 is a central component of the complement system, an essential part of the innate immune response that aids in the clearance of pathogens and the regulation of inflammation C3 is involved in all three complement pathways (classical, alternative, and lectin), playing a critical role in immune defense by promoting opsonization, cell lysis, and inflammation activation Upon cleavage into C3a and C3b, C3a acts as an inflammatory mediator, and C3b binds to pathogens to mark them for destruction by phagocytes Complement C3 deficiency or dysfunction is associated with various autoimmune diseases, such as systemic lupus erythematosus (SLE), and with susceptibility to infections C3 is also involved in the regulation of adaptive immunity, influencing antibody production and T-cell responses Its role in inflammation, pathogen clearance, and immune system regulation highlights its importance in maintaining immune balance and tissue homeostasis

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