Complement C4 (C4) Antibody
273€ (100 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Name
Complement C4 (C4) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx130746
Tested Applications
WB
Description
Complement C4 (C4) Antibody is a Rabbit Polyclonal against Complement C4 (C4).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Complement C4 (C4) Immunogen: C4 (Gln126-Ser366) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 0.01-2 µg/ml, IHC (Predicted): 5-20 µg/ml, IF/ICC (Predicted): 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Purification | Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography. |
| Size 1 | 100 µl |
| Size 2 | 200 µl |
| Size 3 | 1 ml |
| Form | Liquid |
| Tested Applications | WB |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01029 |
| Alias | C4,RG,C4S,CO4,C4A2,C4A3,C4A4,C4A6,C4AD,CPAMD2,Acidic complement C4,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 2 |
| Background | Antibody anti-C4A |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
Complement C4A (Chido/Rodgers blood group) is a component of the classical complement pathway, which plays a crucial role in immune defense and inflammation C4A is involved in the formation of the C3 convertase complex, which leads to the activation of the complement cascade, promoting opsonization, pathogen destruction, and inflammation The Chido and Rodgers antigens are variants of C4A that are of clinical interest due to their association with blood transfusion reactions and their use as markers in blood group systems Complement C4A, along with C4B, contributes to the body's ability to fight infections, clear immune complexes, and resolve inflammation Dysregulation of C4A has been implicated in autoimmune diseases, such as lupus, where complement activation exacerbates tissue damage and inflammation C4A also influences immune responses to cancer, where its role in immune complex clearance can impact tumor progression and metastasis Understanding C4A and its polymorphisms is crucial for improving clinical approaches to immune modulation and blood group testing
Productos relacionados
Complement Component C4 Beta Chain (C4-beta) Antibody
Complement C4 beta chain Antibody is a Rabbit Polyclonal antibody against Human.…
Ver producto
Complement C4 (C4) Antibody
Complement C4 Antibody is a Goat polyclonal antibody for proteins and bioactive peptides against Complement C4.…
Ver producto Complement C4 (C4) Antibody
Complement C4 Antibody is a Goat polyclonal antibody for proteins and bioactive peptides against Complement C4.…
Ver producto