Complement C4-B (C4B) Antibody (FITC)

Pida mas información
935106861
info@markelab.com
Precio
442€ (200 µl)
Antibody anti-C4B
proveedor
Abbexareference
abx273939Tested Applications
WB, IHC, IF/ICCreactivity
Mousestatus
RUOclonality
PolyclonalDescripción
Complement C4 (C4) Antibody (FITC) is a Rabbit Polyclonal antibody conjugated to FITC against Complement C4 (C4).
Background
C4B is a component of the classical and lectin pathways of the complement system, which plays an essential role in immune defense by promoting pathogen clearance, inflammation, and immune complex removal C4B is involved in the formation of the C3 convertase complex, which activates the complement cascade and results in the destruction of pathogens via opsonization and lysis It also participates in the regulation of immune responses and plays a role in clearing immune complexes that could otherwise contribute to tissue damage C4B is implicated in the Chido/Rodgers blood group system, which is used in transfusion medicine C4B deficiency or dysfunction is associated with autoimmune diseases, including systemic lupus erythematosus, where excessive complement activation exacerbates tissue damage The balance of C4B in the complement system is crucial for maintaining immune homeostasis and preventing chronic inflammation
Características del producto
category
Primary Antibodies
clonality
Polyclonal
reactivity
Mouse
immunogen target
Complement C4 (C4)
host
Rabbit
isotype
IgG
conjugation
FITC
form
Liquid
tested applications
WB, IHC, IF/ICC
purification
Purified by antigen-specific affinity chromatography.
recommended dilution
WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
buffer
0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol.
size 1
200 µl
size 2
1 ml
storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
or code
C4B
dry ice
No
availability
Shipped within 5-15 working days.
alias
CH,C4F,CO4,C4B1,C4B2,C4B3,C4B5,C4BD,C4B12,C4B_2,CPAMD3,Basic complement C4,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3
uniprot id
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