Complement C4a anaphylatoxin (C4a) Antibody (Biotin)
377€ (200 µl)
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935106861
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name
Complement C4a anaphylatoxin (C4a) Antibody (Biotin)
category
Primary Antibodies
provider
Abbexa
reference
abx272777
tested applications
WB, IHC, IF/ICC
Description
Complement Fragment C4a (C4a) Antibody (Biotin) is a polyclonal antibody conjugated to Biotin against Complement Fragment C4a (C4a).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Complement C4a anaphylatoxin (C4a) |
| Host | Rabbit |
| Reactivity | Mouse |
| Recommended Dilution | WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 200 µl |
| Size 2 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P01029 |
| Gene ID | 12268 |
| Alias | CH,C4F,CO4,C4B1,C4B2,C4B3,C4B5,C4BD,C4B12,C4B_2,CPAMD3,Basic complement C4,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3 |
| Background | Antibody anti-C4A |
| Status | RUO |
| Note | Concentration: 0.44 mg/ml - |
Descripción
C4B is a component of the classical and lectin pathways of the complement system, which plays an essential role in immune defense by promoting pathogen clearance, inflammation, and immune complex removal C4B is involved in the formation of the C3 convertase complex, which activates the complement cascade and results in the destruction of pathogens via opsonization and lysis It also participates in the regulation of immune responses and plays a role in clearing immune complexes that could otherwise contribute to tissue damage C4B is implicated in the Chido/Rodgers blood group system, which is used in transfusion medicine C4B deficiency or dysfunction is associated with autoimmune diseases, including systemic lupus erythematosus, where excessive complement activation exacerbates tissue damage The balance of C4B in the complement system is crucial for maintaining immune homeostasis and preventing chronic inflammation
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