Complement C4 Gamma Chain (C4 gamma) Antibody

Este producto es parte de Complement C4B (Chido/Rodgers blood group)
Complement C4 Gamma Chain (C4 gamma) Antibody

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935106861

info@markelab.com

Precio

169€ (20 µg)

Antibody anti-C4B

proveedor

Abbexa

reference

abx109270

Tested Applications

ELISA, IHC

reactivity

Human

status

RUO

clonality

Polyclonal

Descripción

Complement C4 Gamma Chain (C4 gamma) Antibody is a Rabbit Polyclonal antibody against Complement C4 Gamma Chain (C4gamma).


Background

C4B is a component of the classical and lectin pathways of the complement system, which plays an essential role in immune defense by promoting pathogen clearance, inflammation, and immune complex removal C4B is involved in the formation of the C3 convertase complex, which activates the complement cascade and results in the destruction of pathogens via opsonization and lysis It also participates in the regulation of immune responses and plays a role in clearing immune complexes that could otherwise contribute to tissue damage C4B is implicated in the Chido/Rodgers blood group system, which is used in transfusion medicine C4B deficiency or dysfunction is associated with autoimmune diseases, including systemic lupus erythematosus, where excessive complement activation exacerbates tissue damage The balance of C4B in the complement system is crucial for maintaining immune homeostasis and preventing chronic inflammation

Características del producto

category

Primary Antibodies


clonality

Polyclonal


reactivity

Human


immunogen target

Complement C4 Gamma Chain (C4 gamma)


host

Rabbit


isotype

IgG


conjugation

Unconjugated


form

Liquid


tested applications

ELISA, IHC


purity

> 95%


purification

Purified by Protein G.


recommended dilution

IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.


buffer

0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.


size 1

20 µg


size 2

50 µg


size 3

100 µg


size 4

200 µg


size 5

1 mg


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

C4B


dry ice

No


availability

Shipped within 5-10 working days.


alias

CH,C4F,CO4,C4B1,C4B2,C4B3,C4B5,C4BD,C4B12,C4B_2,CPAMD3,Basic complement C4,C3 and PZP-like alpha-2-macroglobulin domain-containing protein 3


note

Concentration: 3 mg/ml -


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