Cluster of Differentiation 99 (CD99) Antibody (FITC)
208€ (25 µg)
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935106861
info@markelab.com
name
Cluster of Differentiation 99 (CD99) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx413431
tested applications
FCM
Description
T-Cell Surface Glycoprotein E2 (CD99) Antibody (FITC) is a Mouse Monoclonal antibody against T-Cell Surface Glycoprotein E2 (CD99).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cluster of Differentiation 99 (CD99) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG1 |
| Purification | Purified |
| Size 1 | 25 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | PBS, 1% BSA. Contains sodium azide. |
| Availability | Shipped within 3-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P14209 |
| Alias | Xg blood group,MIC2,HBA71,MIC2X,MIC2Y,MSK5X,Protein MIC2,T-cell surface glycoprotein E2 |
| Background | Antibody anti-CD99 |
| Status | RUO |
| Note | Concentration: 0.1 mg/ml - |
Descripción
CD99, also known as MIC2, is a cell surface glycoprotein expressed on various cell types, including leukocytes, endothelial cells, and certain tumor cells. The CD99 protein plays a role in multiple biological processes, such as cell adhesion, migration, apoptosis, and immune regulation. CD99 expression is crucial in thymocyte differentiation and T cell activation, as well as in leukocyte extravasation, where immune cells move from blood vessels to sites of inflammation. It is also involved in neural cell adhesion and spermatogenesis, highlighting its diverse functional roles across cell types and tissues. CD99 has garnered attention for its clinical implications, especially in cancer, as it is overexpressed in Ewing sarcoma and other tumors, making it a biomarker of diagnostic and therapeutic interest. Additionally, CD99 is involved in the immune response, where it contributes to the regulation of leukocyte activity and inflammation. The molecule also plays a role in apoptosis, promoting cell death in specific contexts, and has a dual role in tumor biology, both enhancing and inhibiting tumor progression depending on the cancer type and tissue context.
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