Cluster of Differentiation 82 (CD82) Antibody (FITC)
364€ (100 tests)
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935106861
info@markelab.com
name
Cluster of Differentiation 82 (CD82) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx139661
tested applications
FCM
Description
CD82 Antibody is a Mouse Monoclonal against CD82.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cluster of Differentiation 82 (CD82) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | FCM: 4 µl/100 µl of whole blood or 106 cells. Validated in IHC-P and ICC. Optimal dilutions/concentrations should be determined by the end user. The content of a vial (0.4 ml) is sufficient for 100 tests. |
| Clonality | Monoclonal |
| Conjugation | FITC |
| Isotype | IgG2a |
| Clone ID | V739 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P27701 |
| Gene ID | 3732 |
| Alias | R2,4F9,C33,IA4,ST6,GR15,KAI1,SAR2,TSPAN27,CD82 antigen,Inducible membrane protein R2,Metastasis suppressor Kangai-1,Suppressor of tumorigenicity 6 protein,Tetraspanin-27 |
| Background | Antibody anti-CD82 |
| Status | RUO |
Descripción
CD82, also known as KAI1 (Kangai 1), is a member of the tetraspanin family, a group of integral membrane proteins involved in the regulation of cell development, motility, adhesion, and immune responses. CD82 is of particular interest in cancer biology due to its role as a metastasis suppressor gene. It was initially identified as a tumor suppressor in prostate cancer, and subsequent studies have demonstrated that it plays a significant role in suppressing metastasis across a range of cancers. The CD82 gene is located on chromosome 11p11.2 and is ubiquitously expressed in various cell types, including epithelial cells, immune cells, and neurons. The primary function of CD82 is to regulate cell-cell interactions and modulate signal transduction pathways. Importantly, CD82 is involved in the regulation of immune cell activation, adhesion, and migration, making it a vital component in both immune responses and cancer progression.
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