Cluster of Differentiation 8 (CD8) Antibody
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Description
CD8 Antibody is a Mouse monoclonal antibody for human cds against CD8.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cluster of Differentiation 8 (CD8) |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG2a Kappa |
| Purification | Purified from ascites. |
| Size 1 | 1 mg |
| Form | Liquid |
| Buffer | Buffer contains NaN3 as a preservative. |
| Availability | Shipped within 10-20 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Background | Antibody anti-CD8 |
| Status | RUO |
Descripción
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CD8 T cell surface antigen is heterodimer of an alpha and a beta chain linked by two disulfide bonds.It belongs type I membrane protein.Selectively expressing of CD8 on a subset of T cells leads to CD8 T cell development.Through identifying cytotoxic/suppressor T-cells that interact with MHC class I bearing targets, CD8 is thought to play a role in the process of T-cell mediated killing.Veillette et al (1988) found the CD8 is associated with the internal membrane tyrosine- protein kinase p56lck.
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