Cluster of Differentiation 44 Variant 5 (CD44v5) Antibody

Este producto es parte de CD44 - CD44 molecule
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351€ (100 µg)

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935106861
info@markelab.com
name
Cluster of Differentiation 44 Variant 5 (CD44v5) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx413290
tested applications
ELISA, WB, IHC

Description

Cluster of Differentiation 44 Variant 5 (CD44v5) Antibody is a Mouse Monoclonal antibody against Cluster of Differentiation 44 Variant 5 (CD44v5).

Documents del producto

Instrucciones
Data sheet
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Product specifications

CategoryPrimary Antibodies
Immunogen TargetCluster of Differentiation 44 Variant 5 (CD44v5)
HostMouse
ReactivityHuman
Recommended DilutionValidated in IHC-F and IHC-P. Optimal dilutions/concentrations should be determined by the end user.
ClonalityMonoclonal
ConjugationUnconjugated
IsotypeIgG1
PurificationPurified
Size 1100 µg
FormLiquid
Tested ApplicationsELISA, WB, IHC
BufferPBS. Contains sodium azide.
AvailabilityShipped within 3-7 working days.
StorageAliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry IceNo
UniProt IDP16070
AliasIN blood group,LHR,MC56,MIC4,CDW44,CSPG8,H-CAM,HCELL,ECM-III,HUTCH-1,HUTCH-I,ECMR-III,Hermes-1,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor
BackgroundAntibody anti-CD44
StatusRUO
NoteConcentration: 0.1 mg/ml -

Descripción

CD44 is a type I transmembrane glycoprotein and an important cell surface receptor involved in various physiological and pathological processes. It is expressed on a wide range of cells, including hematopoietic cells, epithelial cells, fibroblasts, endothelial cells, and neurons. CD44 plays a crucial role in cell-cell and cell-matrix interactions, facilitating processes such as cell adhesion, migration, proliferation, and differentiation. The most well-studied ligand of CD44 is hyaluronic acid (HA), a major component of the extracellular matrix (ECM), which mediates a variety of cellular responses. CD44 is implicated in numerous biological processes, including immune response modulation, tissue repair, inflammation, and cancer metastasis. The molecule is often referred to as a "stem cell marker" due to its elevated expression in several types of cancer stem cells.

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