Cluster of Differentiation 3d (CD3D) Antibody (Biotin)
429€ (200 µl)
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Name
Cluster of Differentiation 3d (CD3D) Antibody (Biotin)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx273487
Tested Applications
WB, IHC, IF/ICC
Description
Cluster Of Differentiation 3d (CD3d) Antibody (Biotin) is a Rabbit Polyclonal antibody conjugated to Biotin against Cluster Of Differentiation 3d (CD3d).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Cluster of Differentiation 3d (CD3D) |
| Host | Rabbit |
| Reactivity | Pig |
| Recommended Dilution | WB: 0.5-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Biotin |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 200 µl |
| Size 2 | 1 ml |
| Form | Liquid |
| Tested Applications | WB, IHC, IF/ICC |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | T3D,IMD19,CD3DELTA,CD3-DELTA,T-cell surface glycoprotein CD3 delta chain,T-cell receptor T3 delta chain |
| Background | Antibody anti-CD3D |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD3D, the delta subunit of the T-cell receptor (TCR) complex, plays a critical role in T-cell development and activation, which are essential components of the adaptive immune system. The TCR complex is responsible for recognizing antigens presented by major histocompatibility complex (MHC) molecules on the surface of antigen-presenting cells (APCs), allowing T-cells to initiate immune responses against pathogens. The CD3D subunit, along with other CD3 subunits (CD3E, CD3G, and CD3Z), functions as part of the CD3 complex, which couples with the TCR α/β heterodimer to mediate signal transduction following antigen recognition. The CD3D gene, located on chromosome 11q23, encodes the CD3δ chain, a 20-25 kDa protein essential for the assembly and function of the TCR complex. The CD3 complex, including the CD3D subunit, is expressed in all T lymphocytes and plays a vital role in transmitting signals from the extracellular environment to the interior of the cell, initiating downstream signaling cascades essential for T-cell activation, differentiation, and survival.
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