Cluster of Differentiation 226 (CD226) Antibody
806€ (1 mg)
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Name
Cluster of Differentiation 226 (CD226) Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx413923
Tested Applications
FCM, IP
Description
DNAX Accessory Molecule-1 (CD226) Antibody is a Mouse Monoclonal antibody against DNAX Accessory Molecule-1 (CD226).
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: Cluster of Differentiation 226 (CD226) |
| Host | Mouse |
| Reactivity | Human |
| Assay Type | Concentration: 1.0 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Unconjugated |
| Isotype | IgG1 |
| Purification | Purified |
| Size 1 | 1 mg |
| Form | Liquid |
| Tested Applications | FCM, IP |
| Buffer | PBS. |
| Availability | Shipped within 3-7 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q15762 |
| Alias | PTA1,DNAM1,DNAM-1,TLiSA1,DNAX accessory molecule 1 |
| Background | Antibody anti-CD226 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD226, also known as DNAX Accessory Molecule-1 (DNAM-1), is a critical glycoprotein that plays a significant role in the immune system. It is encoded by the CD226 gene located on chromosome 18q22.3. This molecule is predominantly expressed on the surface of various immune cells, including natural killer (NK) cells, T cells, monocytes, and platelets. The expression of CD226 is crucial for the regulation and activation of immune responses against tumors and infections. CD226 was initially identified due to its involvement in the adhesion and activation of NK cells and T cells. Its significance has expanded to various immunological processes, including cytotoxicity, cytokine production, and immune cell signaling. The interaction of CD226 with its ligands, such as CD155 (PVR) and CD112 (Nectin-2), is vital for the mediation of immune responses.
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