Cluster of Differentiation 160 (CD160) Antibody (FITC)
494€ (100 tests)
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935106861
info@markelab.com
name
Cluster of Differentiation 160 (CD160) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx270373
tested applications
FCM
Description
Cluster Of Differentiation 160 (CD160) Antibody (FITC) is a Rabbit Polyclonal Antibody conjugated to FITC against Cluster Of Differentiation 160 (CD160) for use in flow cytometry.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cluster of Differentiation 160 (CD160) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | FCM: 1-5 µl/106 cells. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | FITC |
| Isotype | IgG |
| Purification | Purified by antigen-specific affinity chromatography. |
| Size 1 | 100 tests |
| Size 2 | 200 tests |
| Size 3 | 500 tests |
| Form | Liquid |
| Tested Applications | FCM |
| Buffer | 0.01 M PBS, pH 7.4, containing 0.05% Proclin-300, 50% glycerol. |
| Availability | Please enquire. |
| Storage | Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| Alias | NK1,BY55,NK28,Natural killer cell receptor BY55 |
| Background | Antibody anti-CD160 |
| Status | RUO |
Descripción
The CD160 molecule, encoded by the CD160 gene, is a glycoprotein primarily expressed on the surface of cytotoxic lymphocytes, including natural killer (NK) cells, NKT cells, a subset of CD8+ T cells, and certain peripheral blood T-cell populations. CD160 was first identified for its unique expression pattern on immune cells and its role in modulating cytotoxic activity, playing a critical role in immune response against tumors and infected cells. CD160 functions as a receptor that binds to a variety of ligands, notably major histocompatibility complex (MHC) class I molecules and herpesvirus entry mediator (HVEM), both of which have implications in immune activation and inhibition. CD160 serves as an immune checkpoint, similar to other co-inhibitory receptors such as CTLA-4 and PD-1, and its signaling is implicated in modulating immune responses. Its functions in immune surveillance and regulation make it particularly significant in oncology, viral immunology, and autoimmune disorders. CD160 is also characterized by its restricted expression on peripheral blood monocytes and on cells in the gastrointestinal tract, indicating its broader role in tissue-specific immune responses and homeostasis.
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