Chromobox Protein Homolog 1 (CBX1) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
CBX1 Antibody is a Rabbit Polyclonal against CBX1.
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Chromobox Protein Homolog 1 (CBX1) |
| Host | Rabbit |
| Reactivity | Human, Mouse |
| Recommended Dilution | ELISA: 1/1000 - 1/2000, IHC: 1/15 - 1/50. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Antigen Affinity Chromatography. |
| Size 1 | 50 µl |
| Size 2 | 100 µl |
| Form | Liquid |
| Tested Applications | ELISA, IHC |
| Buffer | PBS, pH 7.4, containing 0.05% NaN3 and 40% Glycerol. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P83916 |
| Gene ID | 10951 |
| Background | Antibody anti-CBX1 |
| Status | RUO |
Descripción
Related Products
CBX1 antibody
Component of heterochromatin. Recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. Interaction with lamin B receptor(LBR) can contribute to the association of the heterochromatin with the inner nuclear membrane.
Ver Producto
Recombinant Human CBX1
Ver Producto
Chromobox Protein Homolog 1 (CBX1) Antibody
CBX1 Antibody is a Rabbit Polyclonal antibody against CBX1. This gene encodes a highly conserved nonhistone protein, which is a member of the heterochromatin protein family. The protein is enriched in the heterochromatin and associated with centromeres. The protein has a single N-terminal chromodomain which can bind to histone proteins via methylated lysine residues, and a C-terminal chromo shadow-domain (CSD) which is responsible for the homodimerization and interaction with a number of chromatin-associated nonhistone proteins. The protein may play an important role in the epigenetic control of chromatin structure and gene expression. Several related pseudogenes are located on chromosomes 1, 3, and X. Multiple alternatively spliced variants, encoding the same protein, have been identified.
Ver Producto