Chromatin Assembly Factor 1 Subunit A (CHAF1A) Antibody
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Description
Chromatin Assembly Factor 1 Subunit A (CHAF1A) Antibody is a Rabbit polyclonal antibody for the detection of Human Chromatin Assembly Factor 1 Subunit A (CHAF1A).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Chromatin Assembly Factor 1 Subunit A (CHAF1A) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | Q13111 |
| Gene ID | 10036 |
| NCBI Accession | NP_005474.2 |
| Background | Antibody anti-CHAF1A |
| Status | RUO |
Descripción
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Core component of the CAF-1 complex, a complex thought to mediate chromatin assembly in DNA replication and DNA repair. Assembles histone octamers onto replicating DNA in vitro. CAF-1 performs the first step of the nucleosome assembly process, bringing newly synthesized histones H3 and H4 to replicating DNA; histones H2A/H2B can bind to this chromatin precursor subsequent to DNA replication to complete the histone octamer. CHAF1A binds to histones H3 and H4. It may play a role in heterochromatin maintenance in proliferating cells by bringing newly synthesized cbx proteins to heterochromatic DNA replication foci(By similarity).
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