Chicken Epithelial Cell Adhesion Molecule (EPCAM) Protein

Este producto es parte de EPCAM - epithelial cell adhesion molecule
Product Graph
442€ (50 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Chicken Epithelial Cell Adhesion Molecule (EPCAM) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx168032
tested applications
WB, SDS-PAGE

Description

Epithelial Cell Adhesion Molecule (EPCAM) Protein is a recombinant Chicken protein expressed in E. coli.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Proteins and Peptides
Immunogen Target
Epithelial Cell Adhesion Molecule (EPCAM)
Host
E. coli
Origin
Chicken
Conjugation
Unconjugated
Observed MW
Molecular Weight: Calculated MW: 32.1 kDa  Observed MW (SDS-PAGE): 36 kDa
Concentration: Prior to lyophilization: 200 µg/ml
Sequence Fragment: Asp21-Gly260 linked with LEHHHHHH
Tag: N-terminal His tag
Expression
Recombinant
Purity
> 97%
Size 1
50 µg
Size 2
100 µg
Size 3
200 µg
Size 4
500 µg
Size 5
1 mg
Form
Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in 20 mM Tris, 150 mM NaCl, pH 8.0. If a higher concentration is required, the product can be reconstituted directly in 20 mM Tris, 150 mM NaCl, pH 8.0, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex.
Tested Applications
WB, SDS-PAGE
Buffer
Prior to lyophilization: 20 mM Tris, 150 mM NaCl, pH 8.0, containing 1 mM EDTA, 1 mM DTT, 0.01% Sarcosyl, 5% Trehalose and Proclin-300.
Availability
Shipped within 5-7 working days.
Storage
Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Alias
ESA,KSA,M4S1,MK-1,DIAR5,EGP-2,EGP40,KS1/4,MIC18,TROP1,TACSTD1,Ep-CAM,Adenocarcinoma-associated antigen,Cell surface glycoprotein Trop-1,Epithelial cell surface antigen
Background
Protein EPCAM
Status
RUO
Note
This product is for research use only.   Not for human consumption, cosmetic, therapeutic or diagnostic use.

Descripción

Epithelial Cell Adhesion Molecule (EPCAM) , also known as CD326 or TACSTD1 (tumor-associated calcium signal transducer 1), is a transmembrane glycoprotein prominently expressed on the surface of epithelial cells in various tissues. EpCAM plays a dual role in cellular adhesion and signaling, as well as in the regulation of cell proliferation and differentiation. Originally identified as a marker on cancer cells, EpCAM is also a vital component in normal epithelial physiology, where it participates in maintaining cell-cell adhesion and the structural integrity of epithelial layers. EpCAM has become a major focus in cancer research due to its high expression in numerous epithelial tumors, including colorectal, breast, lung, and ovarian cancers. It is frequently upregulated in cancer, where it contributes to cell proliferation, migration, and invasion, as well as tumor growth and metastasis. Its presence on circulating tumor cells has made EpCAM a promising biomarker for early cancer detection and prognosis. Beyond its role in oncogenesis, EpCAM is involved in regenerative processes in epithelial tissues, influencing stem cell behavior and tissue repair.

Related Products

APC-30140

APC Anti-Human CD326/EpCAM (9C4)

Ver Producto
EH3005

Human Ep-CAM/CD326 (Epithelial Cell Adhesion Molecule) ELISA Kit

Ver Producto
EM1005

Mouse EPCAM (Epithelial Cell Adhesion Molecule) ELISA Kit

Ver Producto