Chicken Annexin A5 (ANXA5) Protein
390€ (50 µg)
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name
Chicken Annexin A5 (ANXA5) Protein
category
Proteins and Peptides
provider
Abbexa
reference
abx065381
tested applications
WB, SDS-PAGE
Description
Annexin V (ANXA5) is a recombinant Chicken protein produced in a Prokaryotic expression system (E. coli).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Proteins and Peptides |
| Immunogen Target | Annexin A5 (ANXA5) |
| Host | E. coli |
| Origin | Chicken |
| Conjugation | Unconjugated |
| Observed MW | Molecular Weight: Calculated MW: 37.4 kDa Concentration: Prior to lyophilization: 200 µg/ml Sequence Fragment: Met1-Glu321 Tag: N-terminal His tag |
| Expression | Recombinant |
| Purity | > 95% |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Size 3 | 200 µg |
| Size 4 | 500 µg |
| Size 5 | 1 mg |
| Form | Lyophilized To keep the original salt concentration, we recommend reconstituting to the original concentration prior to lyophilization (see Concentration) in ddH2O. If a lower concentration is required, dilute in PBS, pH 7.4. If a higher concentration is required, the product can be reconstituted directly in PBS, pH 7.4, though please note that this will change the overall salt concentration. The stock concentration should be between 0.1-1.0 mg/ml. Do not vortex. |
| Tested Applications | WB, SDS-PAGE |
| Buffer | Prior to lyophilization: PBS, pH 7.4, containing 0.01% Sarcosyl, 1 mM DTT, 5% Trehalose and Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8 °C for up to one month. Store at -80 °C for up to one year. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P17153 |
| Alias | ANXA5,ANX5,ENX2,PP4 |
| Background | Protein ANXA5 |
| Status | RUO |
| Note | This product is for research use only. Not for human consumption, cosmetic, therapeutic or diagnostic use. |
Descripción
ANXA5 is a well-known calcium- and phospholipid-binding protein involved in apoptosis, membrane repair, and anti-inflammatory processes. It binds to phosphatidylserine (PS), a phospholipid exposed on the outer leaflet of apoptotic cells, making ANXA5 a widely used marker for apoptosis detection. ANXA5 regulates coagulation and fibrinolysis by preventing the assembly of coagulation complexes on cell membranes, contributing to antithrombotic activity. It is expressed in various tissues, including the placenta, where it plays roles in trophoblast function and pregnancy maintenance. Dysregulation of ANXA5 has been associated with autoimmune diseases, recurrent pregnancy loss, and cancers. Its apoptotic and anticoagulant properties make it a key protein in cellular homeostasis and disease pathology.
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