Charged Multivesicular Body Protein 2A (CHMP2A) Antibody
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
Description
Charged Multivesicular Body Protein 2A (CHMP2A) Antibody is a Rabbit polyclonal antibody for the detection of Human Charged Multivesicular Body Protein 2A (CHMP2A).
Documents del producto
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Charged Multivesicular Body Protein 2A (CHMP2A) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | O43633 |
| Gene ID | 27243 |
| NCBI Accession | NP_055268.1 |
| Background | Antibody anti-CHMP2A |
| Status | RUO |
Descripción
Related Products
CHMP2A antibody
Probable core component of the endosomal sorting required for transport complex III(ESCRT-III) which is involved in multivesicular bodies(MVBs) formation and sorting of endosomal cargo proteins into MVBs. MVBs contain intraluminal vesicles(ILVs) that are generated by invagination and scission from the limiting membrane of the endosome and mostly are delivered to lysosomes enabling degradation of membrane proteins, such as stimulated growth factor receptors, lysosomal enzymes and lipids. The MVB pathway appears to require the sequential function of ESCRT-O,-I,-II and-III complexes. ESCRT-III proteins mostly dissociate from the invaginating membrane before the ILV is released. The ESCRT machinery also functions in topologically equivalent membrane fission events, such as the terminal stages of cytokinesis(PubMed:21310966). Together with SPAST, the ESCRT-III complex promotes nuclear envelope sealing and mitotic spindle disassembly during late anaphase(PubMed:26040712). ESCRT-III proteins are believed to mediate the necessary vesicle extrusion and/or membrane fission activities, possibly in conjunction with the AAA ATPase VPS4. (Microbial infection) The ESCRT machinery functions in topologically equivalent membrane fission events, such as the budding of enveloped viruses(HIV-1 and other lentiviruses). Involved in HIV-1 p6-and p9-dependent virus release.
Ver Producto
Recombinant Human CHMP2A
Ver Producto
Charged Multivesicular Body Protein 2a (CHMP2A) Antibody (Biotin)
Charged multivesicular body protein 2a Antibody (Biotin) is a Rabbit Polyclonal antibody against Charged multivesicular body protein 2a conjugated to Biotin.
Ver Producto