Centrosomal Protein 63 kDa (CEP63) Antibody (FITC)

Product Graph
169€ (20 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

935106861
info@markelab.com
name
Centrosomal Protein 63 kDa (CEP63) Antibody (FITC)
category
Primary Antibodies
provider
Abbexa
reference
abx309389

Description

CEP63 Antibody (FITC) is a Rabbit Polyclonal against CEP63 conjugated to FITC.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
Centrosomal Protein 63 kDa (CEP63)
Host
Rabbit
Reactivity
Human
Recommended Dilution
Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
FITC
Isotype
IgG
Purity
> 95%
Purification
Purified by Protein G.
Size 1
20 µg
Size 2
50 µg
Size 3
100 µg
Size 4
200 µg
Size 5
1 mg
Form
Liquid
Buffer
0.01 M PBS, pH 7.4, 0.03% Proclin-300 and 50% Glycerol.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid exposure to light. Avoid repeated freeze/thaw cycles.
Dry Ice
No
UniProt ID
Q96MT8
Gene ID
80254
NCBI Accession
NP_001035842.1, NM_001042383.1, NP_001035843.1, NM_001042384.1, NP_001035859.1, NM_001042400.1, NP_079456.2, NM_025180.3
OMIM
614724
Background
Antibody anti-CEP63
Status
RUO

Descripción

Related Products

FNab01606

CEP63 antibody

Required for normal spindle assembly. Plays a key role in mother-centriole-dependent centriole duplication; the function seems also to involve CEP152, CDK5RAP2 and WDR62 through a stepwise assembled complex at the centrosome that recruits CDK2 required for centriole duplication. Reported to be required for centrosomal recruitment of CEP152; however, this function has been questioned(PubMed:21983783, PubMed:26297806). Also recruits CDK1 to centrosomes(PubMed:21406398). Plays a role in DNA damage response. Following DNA damage, such as double-strand breaks(DSBs), is removed from centrosomes; this leads to the inactivation of spindle assembly and delay in mitotic progression(PubMed:21406398).

Ver Producto
P2465

Recombinant Human CEP63

Ver Producto
abx032314

Centrosomal Protein 63 kDa (CEP63) Antibody

CEP63 is a protein with six coiled-coil domains. The protein is localized to the centrosome, a non-membraneous organelle that functions as the major microtubule-organizing center in animal cells.

Ver Producto