Cellular Tumor Antigen P53 (p53) Antibody (ATTO594)
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Description
p53 Antibody (ATTO594) is a Rabbit Polyclonal against p53.
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cellular Tumor Antigen P53 (p53) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | WB: 1/1000, IF/ICC: 1/100. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | ATTO594 |
| Purification | Peptide Affinity Purified |
| Size 1 | 100 µg |
| Tested Applications | WB, IF/ICC |
| Buffer | PBS, 50% glycerol, 0.09% sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P04637 |
| Gene ID | 7157 |
| NCBI Accession | NP_000537.3 |
| Background | Antibody anti-p53 |
| Status | RUO |
| Note | Concentration: 1 mg/ml - |
Descripción
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p53 (pS15) Antibody is a Rabbit Polyclonal antibody against p53 (pS15). This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).
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