Cell Division Control Protein 42 Homolog (CDC42) Antibody
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Description
Cell Division Control Protein 42 Homolog (CDC42) Antibody is a Rabbit polyclonal antibody for the detection of Human Cell Division Control Protein 42 Homolog (CDC42).
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Product specifications
| Category | Primary Antibodies |
| Immunogen Target | Cell Division Control Protein 42 Homolog (CDC42) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P60953 |
| Gene ID | 998 |
| NCBI Accession | NP_001034891.1 |
| Background | Antibody anti-CDC42 |
| Status | RUO |
Descripción
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Human CDC42 (Cell division control protein 42 homolog) ELISA Kit
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CDC42 antibody
The protein encoded by this gene is a small GTPase of the Rho-subfamily, which regulates signaling pathways that control diverse cellular functions including cell morphology, migration, endocytosis and cell cycle progression. This protein is highly similar to Saccharomyces cerevisiae Cdc 42, and is able to complement the yeast cdc42-1 mutant. The product of oncogene Dbl was reported to specifically catalyze the dissociation of GDP from this protein. This protein could regulate actin polymerization through its direct binding to Neural Wiskott-Aldrich syndrome protein (N-WASP), which subsequently activates Arp2/3 complex. Alternative splicing of this gene results in multiple transcript variants. Pseudogenes of this gene have been identified on chromosomes 3, 4, 5, 7, 8 and 20.
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