CD97 Antigen (ADGRE5) Antibody (FITC)

Este producto es parte de ADGRE - Adhesion G protein-coupled receptor E
CD97 Antigen (ADGRE5) Antibody (FITC)

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935106861

info@markelab.com

Precio

475€ (100 µg)

Antibody anti-ADGRE5

proveedor

Abbexa

reference

abx413473

Tested Applications

FCM

reactivity

Human

status

RUO

clonality

Monoclonal

Descripción

Cluster of Differentiation 97 (CD97) Antibody (FITC) is a Mouse Monoclonal antibody against Cluster of Differentiation 97 (CD97).


Background

Adhesion G protein-coupled receptor E5 (ADGRE5), also known as CD97, is a member of the adhesion GPCR family and plays an essential role in cell-cell and cell-matrix interactions. ADGRE5 is highly expressed in immune cells, including macrophages, neutrophils, and T-cells, as well as in endothelial and epithelial cells, where it mediates adhesion, migration, and cellular activation. It is a heterodimeric receptor that interacts with extracellular matrix proteins and cellular ligands such as CD55 (decay-accelerating factor), enabling immune surveillance and inflammation regulation. ADGRE5 is upregulated during inflammation, infection, and cancer progression, contributing to leukocyte recruitment, angiogenesis, and metastasis. Dysregulation of ADGRE5 is associated with autoimmune diseases, such as rheumatoid arthritis and inflammatory bowel disease, and its expression levels are linked to tumor aggressiveness in cancers like glioblastoma and colorectal cancer. Therapeutic targeting of ADGRE5 is being explored as a strategy to modulate immune responses and inhibit tumor metastasis by disrupting its signaling pathways and ligand interactions.

Características del producto

category

Primary Antibodies


clonality

Monoclonal


reactivity

Human


immunogen target

CD97 Antigen (ADGRE5)


host

Mouse


conjugation

FITC


form

Liquid


tested applications

FCM


purification

Purified


buffer

PBS, 1% BSA. Contains sodium azide.


size 1

100 µg


storage

Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.


or code

ADGRE5


dry ice

No


availability

Shipped within 3-7 working days.


alias

ADGRE5,CD97,BL-Ac (F2),CD97,TM7LN1


note

This product is for research use only.


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