CD9 Antigen (CD9) Antibody (Biotin)
247€ (0.1 mg)
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Name
CD9 Antigen (CD9) Antibody (Biotin)
Category
Primary Antibodies
Provider
Abbexa
Reference
abx140027
Tested Applications
WB, IF/ICC, FCM, IP
Description
CD9 Antibody is a Rat Monoclonal against CD9.
Documentos del producto
Instrucciones
Data sheet
Especificaciones del producto
| Category | Primary Antibodies |
| Immunogen Target | Target: CD9 Antigen (CD9) Immunogen: Permeabilized murine bone marrow-derived mast cells (BMMC). |
| Host | Rat |
| Reactivity | Mouse |
| Assay Type | Concentration: 1 mg/ml |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | Biotin |
| Isotype | IgG1 |
| Clone ID | S921 |
| Size 1 | 0.1 mg |
| Tested Applications | WB, IF/ICC, FCM, IP |
| Buffer | PBS solution with 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store at 2-8°C. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P40240 |
| Gene ID | 12527 |
| Alias | MIC3,MRP-1,BTCC-1,DRAP-27,TSPAN29,TSPAN-29,Tetraspanin-29,Motility-related protein,Leukocyte antigen MIC3,Cell growth-inhibiting gene 2 protein,5H9 antigen |
| Background | Antibody anti-CD9 |
| Status | RUO |
| Note | THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION. |
Background
CD9 is a member of the tetraspanin superfamily, a group of transmembrane proteins involved in various biological processes, particularly in cell adhesion, migration, proliferation, and signaling. CD9 is ubiquitously expressed on the surface of various cell types, including platelets, leukocytes, epithelial cells, endothelial cells, and germ cells. It plays a critical role in cell-cell interactions, especially in the context of immune responses, reproduction, cancer metastasis, and viral infection. One of the unique features of tetraspanins, including CD9, is their ability to organize membrane microdomains known as tetraspanin-enriched microdomains (TEMs). These microdomains function as platforms that regulate the spatial organization of other membrane proteins such as integrins, growth factor receptors, and co-receptors, thus modulating their signaling activity. CD9, in particular, interacts with several key molecules, including integrins (α6β1, α3β1), epidermal growth factor receptor (EGFR), and immunoglobulin superfamily proteins.
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