CD9 Antigen (CD9) Antibody
292.5€ (50 µl)
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name
CD9 Antigen (CD9) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx028338
tested applications
ELISA, WB, IHC, IF/ICC
Description
CD9 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. This protein is a cell surface glycoprotein that is known to complex with integrins and other transmembrane 4 superfamily proteins. It can modulate cell adhesion and migration and also trigger platelet activation and aggregation. In addition, the protein appears to promote muscle cell fusion and support myotube maintenance.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CD9 Antigen (CD9) |
| Host | Rabbit |
| Reactivity | Human, Rat |
| Recommended Dilution | WB: 1/1000, IHC-P: 1/100, IF/ICC: 1/25. Not tested in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Purification | Purified Rabbit Polyclonal Antibody. |
| Size 1 | 50 µl |
| Size 2 | 200 µl |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC, IF/ICC |
| Buffer | PBS containing 0.09% sodium azide. |
| Availability | Shipped within 5-10 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P21926 |
| NCBI Accession | NP_001760.1 |
| Alias | MIC3,MRP-1,BTCC-1,DRAP-27,TSPAN29,TSPAN-29,Tetraspanin-29,Motility-related protein,Leukocyte antigen MIC3,Cell growth-inhibiting gene 2 protein,5H9 antigen |
| Background | Antibody anti-CD9 |
| Status | RUO |
Descripción
CD9 is a member of the tetraspanin superfamily, a group of transmembrane proteins involved in various biological processes, particularly in cell adhesion, migration, proliferation, and signaling. CD9 is ubiquitously expressed on the surface of various cell types, including platelets, leukocytes, epithelial cells, endothelial cells, and germ cells. It plays a critical role in cell-cell interactions, especially in the context of immune responses, reproduction, cancer metastasis, and viral infection. One of the unique features of tetraspanins, including CD9, is their ability to organize membrane microdomains known as tetraspanin-enriched microdomains (TEMs). These microdomains function as platforms that regulate the spatial organization of other membrane proteins such as integrins, growth factor receptors, and co-receptors, thus modulating their signaling activity. CD9, in particular, interacts with several key molecules, including integrins (α6β1, α3β1), epidermal growth factor receptor (EGFR), and immunoglobulin superfamily proteins.
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