CD68 Antibody
429€ (100 tests)
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935106861
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name
CD68 Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx140493
tested applications
FCM
Description
CD68 Antibody is a Mouse Monoclonal Antibody against CD68.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CD68 |
| Host | Mouse |
| Reactivity | Human |
| Recommended Dilution | FCM: 10 μl/100 μl of whole blood or 106 cells in a suspension. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | APC |
| Isotype | IgG2a |
| Clone ID | P544 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P34810 |
| Gene ID | 968 |
| Alias | GP110,LAMP4,SCARD1,Macrosialin |
| Background | Antibody anti-CD68 |
| Status | RUO |
Descripción
CD68 is a glycoprotein primarily expressed by cells of the monocyte/macrophage lineage. It belongs to the family of lysosomal-associated membrane proteins (LAMPs) and is widely used as a marker for macrophages, monocytes, dendritic cells, and other myeloid lineage cells. Although CD68 is predominantly associated with immune system cells, it is also found in some non-hematopoietic tissues and other cell types under certain conditions, such as fibroblasts and endothelial cells. This broad expression pattern supports its diverse role in cellular processes like phagocytosis, cell adhesion, and antigen presentation. CD68 is heavily involved in macrophage biology, specifically in processes like scavenging cellular debris, tissue remodeling, and immune surveillance. This protein plays a significant role in the clearance of pathogens and apoptotic cells, contributing to immune homeostasis. It is mainly located in lysosomes and endosomes, though it can also be present on the plasma membrane.
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