High Affinity Immunoglobulin Gamma Fc Receptor I / CD64 (FCGR1A) Antibody (AF647)
117€ (20 tests)
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935106861
info@markelab.com
name
High Affinity Immunoglobulin Gamma Fc Receptor I / CD64 (FCGR1A) Antibody (AF647)
category
Primary Antibodies
provider
Abbexa
reference
abx228742
tested applications
FCM
Description
CD64 Antibody (AF647) is a Human Monoclonal Antibody against CD64.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | High Affinity Immunoglobulin Gamma Fc Receptor I / CD64 (FCGR1A) |
| Host | Mouse |
| Reactivity | Human |
| Clonality | Monoclonal |
| Conjugation | AF647 |
| Isotype | IgG1 |
| Size 1 | 20 tests |
| Size 2 | 100 tests |
| Size 3 | 200 tests |
| Tested Applications | FCM |
| Buffer | PBS with 0.05% Proclin300, 1% BSA. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P12314 |
| Gene ID | 2209 |
| OMIM | 146760 |
| Alias | CD64,FCG1,FCRI,CD64A,FCGR1,IGFR1,FcgammaRI,High affinity immunoglobulin gamma Fc receptor I,IgG Fc receptor I,Fc-gamma RIA |
| Background | Antibody anti-FCGR1A |
| Status | RUO |
Descripción
FCGR1A (Fc gamma receptor Ia), also known as CD64, is a high-affinity receptor for the Fc region of immunoglobulin G (IgG) antibodies. It plays a crucial role in immune responses by binding to the Fc portion of IgG, mediating various immune functions such as phagocytosis, antibody-dependent cellular cytotoxicity (ADCC), and immune complex clearance. FCGR1A is predominantly expressed on monocytes, macrophages, and dendritic cells, as well as on neutrophils during inflammatory responses. The interaction between FCGR1A and IgG antibodies bridges innate and adaptive immunity, facilitating the elimination of pathogens and other foreign particles. It is also critical in the regulation of immune responses by modulating inflammatory signals. FCGR1A is involved in the recognition of opsonized particles, initiating signaling cascades that result in cytokine production, phagocytosis, and the clearance of immune complexes.
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High Affinity Immunoglobulin Gamma Fc Receptor I / CD64 (FCGR1A) Antibody
FCGR1A Antibody is a Rabbit Polyclonal antibody against FCGR1A. This gene encodes a protein that plays an important role in the immune response. This protein is a high-affinity Fc-gamma receptor. The gene is one of three related gene family members located on chromosome 1. [provided by RefSeq, Jul 2008].
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