CD63 Antigen (CD63) Antibody

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Description
CD63 Antigen (CD63) Antibody is a Human Monoclonal antibody for the detection of CD63 Antigen (CD63) in Human samples.
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Product specifications
| Category | Primary Antibodies | 
| Immunogen Target | CD63 Antigen (CD63) | 
| Host | Human | 
| Reactivity | Human | 
| Clonality | Monoclonal | 
| Conjugation | Unconjugated | 
| Isotype | IgG1 | 
| Clone ID | M557 | 
| Purity | > 95% | 
| Purification | Purified by Protein A/G affinity chromatography. | 
| Size 1 | 50 µg | 
| Size 2 | 100 µg | 
| Form | Liquid | 
| Tested Applications | ELISA, WB, IHC, FCM | 
| Buffer | 0.01 M PBS, pH 7.4. | 
| Availability | Shipped within 5-12 working days. | 
| Storage | Store at 4 °C if the entire vial will be used within 1 week. Aliquot and store at -20 °C or -80 °C for long-term storage. Avoid repeated freeze-thaw cycles. | 
| Dry Ice | No | 
| UniProt ID | P08962 | 
| Gene ID | 967 | 
| NCBI Accession | NP_001244318.1 | 
| OMIM | 155740 | 
| Alias | AD1,MLA1,ME491,HOP-26,OMA81H,Pltgp40,TSPAN30,Granulophysin,Lysosomal-associated membrane protein 3,Melanoma-associated antigen ME491 | 
| Background | Antibody anti-CD63 | 
| Status | RUO | 
| Note | Concentration: 2.03 mg/ml - | 
Descripción
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The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility. The encoded protein is a cell surface glycoprotein that is known to complex with integrins. It may function as a blood platelet activation marker. Deficiency of this protein is associated with Hermansky-Pudlak syndrome. Also this gene has been associated with tumor progression. Alternative splicing results in multiple transcript variants encoding different protein isoforms.
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