CD59 Glycoprotein (CD59) Antibody
260€ (50 µg)
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name
CD59 Glycoprotein (CD59) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx377699
tested applications
ELISA, WB, IHC
Description
CD59 Glycoprotein (CD59) Antibody is a Rabbit polyclonal antibody for the detection of Human CD59 Glycoprotein (CD59).
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CD59 Glycoprotein (CD59) |
| Host | Rabbit |
| Reactivity | Human |
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Polyclonal |
| Conjugation | Unconjugated |
| Isotype | IgG |
| Size 1 | 50 µg |
| Size 2 | 100 µg |
| Form | Liquid |
| Tested Applications | ELISA, WB, IHC |
| Buffer | 0.01 M PBS, pH 7.4, 50% glycerol, 0.05% Proclin-300. |
| Availability | Shipped within 5-12 working days. |
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
| Dry Ice | No |
| UniProt ID | P13987 |
| Gene ID | 966 |
| NCBI Accession | NP_000602.1 |
| Alias | CD59 blood group,1F5,EJ16,EJ30,EL32,G344,MIN1,MIN2,MIN3,MIRL,HRF20,MEM43,MIC11,MSK21,16.3A5,HRF-20,MAC-IP,CD59 glycoprotein,MAC-inhibitory protein,MAC-IP,Membrane attack complex inhibition factor,MACIF |
| Background | Antibody anti-CD59 |
| Status | RUO |
Descripción
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CD59 antibody
Potent inhibitor of the complement membrane attack complex(MAC) action. Acts by binding to the C8 and/or C9 complements of the assembling MAC, thereby preventing incorporation of the multiple copies of C9 required for complete formation of the osmolytic pore. This inhibitor appears to be species-specific. Involved in signal transduction for T-cell activation complexed to a protein tyrosine kinase. The soluble form from urine retains its specific complement binding activity, but exhibits greatly reduced ability to inhibit MAC assembly on cell membranes.
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