CD58 Antibody (Biotin)

Este producto es parte de CD58 - CD58 molecule
CD58 Antibody (Biotin)

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935106861

info@markelab.com

Precio

118.75€ (25 µg)

Antibody anti-CD58

proveedor

Abbexa

reference

abx228632

Tested Applications

FCM

reactivity

Human

status

RUO

clonality

Monoclonal

Descripción

CD58 Antibody (Biotin) is a Human Monoclonal Antibody against CD58.


Background

CD58, also known as Lymphocyte Function-associated Antigen 3 (LFA-3), is a cell surface glycoprotein primarily involved in cell adhesion processes. It plays a critical role in the immune response by mediating the interaction between T cells and antigen-presenting cells (APCs). The CD58 protein is a member of the immunoglobulin (Ig) superfamily and is widely expressed on a variety of cell types, including epithelial cells, endothelial cells, lymphocytes, and dendritic cells. Its main binding partner is CD2, a receptor found on T cells and natural killer (NK) cells. This interaction is essential for the formation of the immune synapse, facilitating the activation of T cells and subsequent immune responses. CD58’s role is especially important in antigen presentation, where it helps T cells to recognize and respond to foreign antigens. The molecule is involved in co-stimulation during T-cell receptor (TCR) engagement, enhancing the immune system's ability to respond to pathogens, tumors, and other immunological challenges.

Características del producto

category

Primary Antibodies


clonality

Monoclonal


reactivity

Human


immunogen target

CD58


host

Mouse


isotype

IgG1


conjugation

Biotin


tested applications

FCM


buffer

PBS with 0.05% Proclin300, 1% BSA.


size 1

25 µg


size 2

100 µg


storage

Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze.


or code

CD58


dry ice

No


availability

Shipped within 5-15 working days.


alias

ag3,LFA3,LFA-3,Lymphocyte function-associated antigen 3,Surface glycoprotein LFA-3


note

This product is for research use only.


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