CD57 Antibody (PE / Cyanine 7)

Este producto es parte de B3GAT1 - beta-1,3-glucuronyltransferase 1
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123.5€ (20 tests)

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935106861
info@markelab.com
name
CD57 Antibody (PE / Cyanine 7)
category
Primary Antibodies
provider
Abbexa
reference
abx228626
tested applications
FCM

Description

CD57 Antibody (PE / Cyanine 7) is a Human Monoclonal Antibody against CD57.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
CD57
Host
Mouse
Reactivity
Human
Clonality
Monoclonal
Conjugation
PE / Cyanine 7
Isotype
IgM
Size 1
20 tests
Size 2
100 tests
Size 3
200 tests
Tested Applications
FCM
Buffer
PBS with 0.05% Proclin300, 1% BSA.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze.
Dry Ice
No
UniProt ID
Q9P2W7
Gene ID
27087
Alias
NK1,CD57,HNK1,LEU7,NK-1,GLCATP,GLCUATP,Galactosylgalactosylxylosylprotein 3-beta-glucuronosyltransferase 1,Beta-1,3-glucuronyltransferase 1,Glucuronosyltransferase P,UDP-GlcUA:glycoprotein beta-1,3-glucuronyltransferase,GlcUAT-P
Background
Antibody anti-B3GAT1
Status
RUO

Descripción

Beta-1,3-Glucuronyltransferase 1 (B3GAT1) is an enzyme encoded by the B3GAT1 gene, which plays a critical role in glycosylation processes. It belongs to the family of glycosyltransferases, a group of enzymes responsible for the biosynthesis of glycosaminoglycans (GAGs) and other complex carbohydrates. Specifically, B3GAT1 is involved in the synthesis of the carbohydrate moiety known as the HNK-1 epitope, a unique glycan structure that is found on several proteins in the nervous system and involved in cell-cell and cell-matrix interactions. The enzyme adds a glucuronic acid moiety to the core glycan structure, which is a crucial step in the formation of these specialized carbohydrate chains. B3GAT1 is particularly important in the central nervous system (CNS), where the HNK-1 epitope is associated with neurodevelopmental processes such as cell adhesion, synaptic plasticity, and neuronal migration. The enzyme is also expressed in other tissues, including lymphoid tissues, indicating a broader role in immune regulation and cell signaling.

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