CD46 Antibody (FITC)
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935106861
info@markelab.com
Precio
350€ (100 tests)
Antibody anti-CD46
proveedor
Abbexareference
abx139739Tested Applications
FCMreactivity
Human, Cowstatus
RUOclonality
MonoclonalDescripción
CD46 Antibody is a Mouse Monoclonal against CD46.
Background
CD46, also known as membrane cofactor protein (MCP), is a transmembrane glycoprotein that serves primarily as a regulatory component of the complement system, protecting host cells from complement-mediated damage. CD46 is widely expressed on almost all nucleated cells and plays a key role in immune regulation, ensuring that the complement system, which is responsible for clearing pathogens, does not attack the body’s own cells. CD46 does this by serving as a cofactor for the proteolytic cleavage of C3b and C4b, two crucial components of the complement pathway, which are inactivated by factor I. In addition to its role in the complement system, CD46 is involved in various immune functions, including modulation of T-cell responses, immune tolerance, and viral entry. Several viruses, such as the measles virus and human herpesvirus 6 (HHV-6), use CD46 as a receptor to gain entry into host cells, highlighting its involvement in viral pathogenesis.
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Human, Cow
immunogen target
CD46
host
Mouse
conjugation
FITC
tested applications
FCM
buffer
Stabilizing PBS solution containing 15 mM sodium azide.
size 1
100 tests
storage
Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze.
or code
CD46
dry ice
No
availability
Shipped within 5-12 working days.
alias
MCP,TLX,AHUS2,MIC10,TRA2.10,Membrane cofactor protein,Trophoblast leukocyte common antigen
uniprot id
note
This product is for research use only.
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