CD44v6 Antibody

377€ (100 µg)
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935106861
info@markelab.com
name
CD44v6 Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx018144
tested applications
ELISA, IHC
Description
CD44v6 Antibody is a Mouse Monoclonal antibody against CD44v6.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies  | 
| Immunogen Target | CD44v6  | 
| Host | Mouse  | 
| Reactivity | Human  | 
| Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user.  | 
| Clonality | Monoclonal  | 
| Conjugation | Unconjugated  | 
| Isotype | IgG1  | 
| Purification | Purified from ascites by Protein A chromatography.  | 
| Size 1 | 100 µg  | 
| Form | Liquid  | 
| Tested Applications | ELISA, IHC  | 
| Buffer | Citrate-Tris-HCl, pH 7.0, with 0.02% Proclin-300.  | 
| Availability | Shipped within 5-10 working days.  | 
| Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.  | 
| Dry Ice | No  | 
| UniProt ID | P16070  | 
| Alias | IN blood group,LHR,MC56,MIC4,CDW44,CSPG8,H-CAM,HCELL,ECM-III,HUTCH-1,HUTCH-I,ECMR-III,Hermes-1,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor  | 
| Background | Antibody anti-CD44  | 
| Status | RUO  | 
| Note | Concentration: 1 mg/ml -  | 
Descripción
CD44 is a type I transmembrane glycoprotein and an important cell surface receptor involved in various physiological and pathological processes. It is expressed on a wide range of cells, including hematopoietic cells, epithelial cells, fibroblasts, endothelial cells, and neurons. CD44 plays a crucial role in cell-cell and cell-matrix interactions, facilitating processes such as cell adhesion, migration, proliferation, and differentiation. The most well-studied ligand of CD44 is hyaluronic acid (HA), a major component of the extracellular matrix (ECM), which mediates a variety of cellular responses. CD44 is implicated in numerous biological processes, including immune response modulation, tissue repair, inflammation, and cancer metastasis. The molecule is often referred to as a "stem cell marker" due to its elevated expression in several types of cancer stem cells.
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