CD44 Antigen (CD44) Antibody (APC)
429€ (100 tests)
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935106861
info@markelab.com
name
CD44 Antigen (CD44) Antibody (APC)
category
Primary Antibodies
provider
Abbexa
reference
abx139283
tested applications
FCM
Description
CD44 Antibody is a Mouse Monoclonal against CD44.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CD44 Antigen (CD44) |
| Host | Mouse |
| Reactivity | Human, Pig, Dog |
| Recommended Dilution | FCM: 10 µl/100 µl of whole blood or 106 cells. Validated in IHC-P. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | APC |
| Isotype | IgG1 |
| Clone ID | W173 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | P16070 |
| Gene ID | 960 |
| Alias | IN blood group,LHR,MC56,MIC4,CDW44,CSPG8,H-CAM,HCELL,ECM-III,HUTCH-1,HUTCH-I,ECMR-III,Hermes-1,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor |
| Background | Antibody anti-CD44 |
| Status | RUO |
Descripción
CD44 is a type I transmembrane glycoprotein and an important cell surface receptor involved in various physiological and pathological processes. It is expressed on a wide range of cells, including hematopoietic cells, epithelial cells, fibroblasts, endothelial cells, and neurons. CD44 plays a crucial role in cell-cell and cell-matrix interactions, facilitating processes such as cell adhesion, migration, proliferation, and differentiation. The most well-studied ligand of CD44 is hyaluronic acid (HA), a major component of the extracellular matrix (ECM), which mediates a variety of cellular responses. CD44 is implicated in numerous biological processes, including immune response modulation, tissue repair, inflammation, and cancer metastasis. The molecule is often referred to as a "stem cell marker" due to its elevated expression in several types of cancer stem cells.
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