CD44 Antigen (CD44) Antibody

637€ (100 µl)
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935106861
info@markelab.com
name
CD44 Antigen (CD44) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx111485
tested applications
ELISA, WB, IHC, IF/ICC
Description
Cd44 Molecule (Indian Blood Group) Antibody is a Rabbit Polyclonal antibody against Cd44 Molecule (Indian Blood Group).
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | CD44 Antigen (CD44) |
Host | Rabbit |
Reactivity | Human, Mouse |
Recommended Dilution | Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Antigen Affinity Chromatography. |
Size 1 | 100 µl |
Form | Liquid |
Tested Applications | ELISA, WB, IHC, IF/ICC |
Buffer | PBS, pH 7.3, containing 0.02% Sodium Azide and 50% Glycerol. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
UniProt ID | P16070 |
Gene ID | 960 |
NCBI Accession | NP_000601.3, NM_000610.3 |
OMIM | 107269 |
Alias | IN blood group,LHR,MC56,MIC4,CDW44,CSPG8,H-CAM,HCELL,ECM-III,HUTCH-1,HUTCH-I,ECMR-III,Hermes-1,Epican,Extracellular matrix receptor III,GP90 lymphocyte homing/adhesion receptor |
Background | Antibody anti-CD44 |
Status | RUO |
Descripción
CD44 is a type I transmembrane glycoprotein and an important cell surface receptor involved in various physiological and pathological processes. It is expressed on a wide range of cells, including hematopoietic cells, epithelial cells, fibroblasts, endothelial cells, and neurons. CD44 plays a crucial role in cell-cell and cell-matrix interactions, facilitating processes such as cell adhesion, migration, proliferation, and differentiation. The most well-studied ligand of CD44 is hyaluronic acid (HA), a major component of the extracellular matrix (ECM), which mediates a variety of cellular responses. CD44 is implicated in numerous biological processes, including immune response modulation, tissue repair, inflammation, and cancer metastasis. The molecule is often referred to as a "stem cell marker" due to its elevated expression in several types of cancer stem cells.
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