CD41 Antibody (PE / Cyanine 5.5)

Pida mas información
935106861
info@markelab.com
Precio
208€ (20 tests)
Antibody anti-ITGA2B
proveedor
Abbexareference
abx228768Tested Applications
FCMreactivity
Humanstatus
RUOclonality
MonoclonalDescripción
CD41 Antibody (PE / Cyanine 5.5) is a Human Monoclonal Antibody against CD41.
Background
ITGA2B, also known as integrin alpha 2b or CD41, is a transmembrane glycoprotein that plays a central role in platelet adhesion and aggregation. It is primarily expressed on platelets and megakaryocytes. Together with integrin beta 3 (ITGB3), ITGA2B forms the αIIbβ3 integrin complex (also known as GPIIb/IIIa), which is the most abundant integrin on the surface of platelets and is crucial for blood clot formation (hemostasis). This receptor mediates platelet aggregation by binding to fibrinogen, von Willebrand factor (vWF), fibronectin, and other adhesive proteins during platelet activation. When platelets are stimulated, the αIIbβ3 complex undergoes a conformational change that allows it to bind its ligands and mediate platelet-platelet interactions.
Características del producto
category
Primary Antibodies
clonality
Monoclonal
reactivity
Human
immunogen target
CD41
host
Mouse
isotype
IgG1
conjugation
PE / Cyanine 5.5
tested applications
FCM
purification
¥
buffer
PBS with 0.05% Proclin300, 1% BSA.
size 1
20 tests
size 2
100 tests
size 3
200 tests
storage
Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze.
or code
ITGA2B
dry ice
No
availability
Shipped within 5-15 working days.
alias
GT,GT1,GTA,CD41,GP2B,HPA3,CD41B,GPIIb,BDPLT2,BDPLT16,PPP1R93,Integrin alpha-Iib,GPalpha IIb (GPIIb),Platelet membrane glycoprotein IIb
uniprot id
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