CD3e Molecule Associated Protein (CD3EAP) Antibody

Este producto es parte de CD3E - CD3 epsilon subunit of T-cell receptor complex
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273€ (200 µl)

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935106861
info@markelab.com
name
CD3e Molecule Associated Protein (CD3EAP) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432472
tested applications
P-ELISA

Description

CD3EAP Antibody is a Goat Polyclonal antibody against CD3EAP.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
CD3e Molecule Associated Protein (CD3EAP)
Host
Goat
Recommended Dilution
P-ELISA: 1/4000. Optimal dilutions/concentrations should be determined by the end user.
Clonality
Polyclonal
Conjugation
Unconjugated
Isotype
IgG
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Size 1
200 µl
Form
Liquid
Tested Applications
P-ELISA
Buffer
Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin.
Availability
Shipped within 5-10 working days.
Storage
Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
Dry Ice
No
Gene ID
10849
NCBI Accession
NP_036231.1
Alias
T3E,TCRE,IMD18,CD3epsilon,T-cell surface glycoprotein CD3 epsilon chain,T-cell surface antigen T3/Leu-4 epsilon chain
Background
Antibody anti-CD3E
Status
RUO
Note
Concentration: 0.5 mg/ml - 

Descripción

CD3E (CD3 epsilon) is one of the key subunits of the T-cell receptor (TCR)-CD3 complex, which is vital for T-cell activation and immune responses. The TCR complex allows T lymphocytes to recognize and respond to antigens presented by major histocompatibility complex (MHC) molecules on antigen-presenting cells (APCs). CD3E plays a critical role in assembling the TCR-CD3 complex and facilitating signal transduction after antigen recognition. The CD3E gene is located on chromosome 11q23 and encodes the CD3ε chain, a type I transmembrane protein essential for the assembly, expression, and signaling function of the TCR. Along with other CD3 subunits (CD3δ, CD3γ, and CD3ζ), CD3E forms part of the signal-transducing complex that transmits signals from the TCR upon antigen engagement. This signal initiates the cascade that leads to T-cell activation, differentiation, and proliferation, all of which are crucial for immune defense against pathogens.

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