CD3e Molecule Associated Protein (CD3EAP) Antibody

273€ (200 µl)
Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.
935106861
info@markelab.com
name
CD3e Molecule Associated Protein (CD3EAP) Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx432472
tested applications
P-ELISA
Description
CD3EAP Antibody is a Goat Polyclonal antibody against CD3EAP.
Documents del producto
Instrucciones
Data sheet
Product specifications
Category | Primary Antibodies |
Immunogen Target | CD3e Molecule Associated Protein (CD3EAP) |
Host | Goat |
Recommended Dilution | P-ELISA: 1/4000. Optimal dilutions/concentrations should be determined by the end user. |
Clonality | Polyclonal |
Conjugation | Unconjugated |
Isotype | IgG |
Purification | Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide. |
Size 1 | 200 µl |
Form | Liquid |
Tested Applications | P-ELISA |
Buffer | Tris saline, pH 7.3, containing 0.02% sodium azide and 0.5% bovine serum albumin. |
Availability | Shipped within 5-10 working days. |
Storage | Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles. |
Dry Ice | No |
Gene ID | 10849 |
NCBI Accession | NP_036231.1 |
Alias | T3E,TCRE,IMD18,CD3epsilon,T-cell surface glycoprotein CD3 epsilon chain,T-cell surface antigen T3/Leu-4 epsilon chain |
Background | Antibody anti-CD3E |
Status | RUO |
Note | Concentration: 0.5 mg/ml - |
Descripción
CD3E (CD3 epsilon) is one of the key subunits of the T-cell receptor (TCR)-CD3 complex, which is vital for T-cell activation and immune responses. The TCR complex allows T lymphocytes to recognize and respond to antigens presented by major histocompatibility complex (MHC) molecules on antigen-presenting cells (APCs). CD3E plays a critical role in assembling the TCR-CD3 complex and facilitating signal transduction after antigen recognition. The CD3E gene is located on chromosome 11q23 and encodes the CD3ε chain, a type I transmembrane protein essential for the assembly, expression, and signaling function of the TCR. Along with other CD3 subunits (CD3δ, CD3γ, and CD3ζ), CD3E forms part of the signal-transducing complex that transmits signals from the TCR upon antigen engagement. This signal initiates the cascade that leads to T-cell activation, differentiation, and proliferation, all of which are crucial for immune defense against pathogens.
Related Products

APC Anti-Mouse CD3E (145-2C11)
Ver Producto
Human CD3E (T-cell surface glycoprotein CD3 epsilon chain) ELISA Kit
Ver Producto