CD326 Antibody (PE)
104€ (50 tests)
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935106861
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name
CD326 Antibody (PE)
category
Primary Antibodies
provider
Abbexa
reference
abx229385
tested applications
FCM
Description
CD326 Antibody (PE) is a Mouse Monoclonal Antibody against CD326.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CD326 |
| Host | Rat |
| Reactivity | Mouse |
| Clonality | Monoclonal |
| Conjugation | PE |
| Isotype | IgG2a Kappa |
| Size 1 | 50 tests |
| Size 2 | 100 tests |
| Size 3 | 200 tests |
| Tested Applications | FCM |
| Buffer | PBS with 0.05% Proclin300, 1% BSA. |
| Availability | Shipped within 5-15 working days. |
| Storage | Aliquot and store at 2°C to 8°C upon receipt. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q99JW5 |
| Gene ID | 17075 |
| Alias | ESA,KSA,M4S1,MK-1,DIAR5,EGP-2,EGP40,KS1/4,MIC18,TROP1,TACSTD1,Ep-CAM,Adenocarcinoma-associated antigen,Cell surface glycoprotein Trop-1,Epithelial cell surface antigen |
| Background | Antibody anti-EPCAM |
| Status | RUO |
Descripción
Epithelial Cell Adhesion Molecule (EPCAM) , also known as CD326 or TACSTD1 (tumor-associated calcium signal transducer 1), is a transmembrane glycoprotein prominently expressed on the surface of epithelial cells in various tissues. EpCAM plays a dual role in cellular adhesion and signaling, as well as in the regulation of cell proliferation and differentiation. Originally identified as a marker on cancer cells, EpCAM is also a vital component in normal epithelial physiology, where it participates in maintaining cell-cell adhesion and the structural integrity of epithelial layers. EpCAM has become a major focus in cancer research due to its high expression in numerous epithelial tumors, including colorectal, breast, lung, and ovarian cancers. It is frequently upregulated in cancer, where it contributes to cell proliferation, migration, and invasion, as well as tumor growth and metastasis. Its presence on circulating tumor cells has made EpCAM a promising biomarker for early cancer detection and prognosis. Beyond its role in oncogenesis, EpCAM is involved in regenerative processes in epithelial tissues, influencing stem cell behavior and tissue repair.
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