CD3ε Antibody

Este producto es parte de CD3E - CD3 epsilon subunit of T-cell receptor complex
Product Graph
104€ (25 µg)

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935106861
info@markelab.com
name
CD3ε Antibody
category
Primary Antibodies
provider
Abbexa
reference
abx228898
tested applications
WB, IHC, IF/ICC, FCM, IP

Description

CD3ε Antibody is a Mouse Monoclonal Antibody against CD3ε.

Documents del producto

Instrucciones
Data sheet
Descargar

Product specifications

Category
Primary Antibodies
Immunogen Target
CD3ε
Host
Hamster
Reactivity
Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG
Size 1
25 µg
Size 2
100 µg
Size 3
1 mg
Tested Applications
WB, IHC, IF/ICC, FCM, IP
Buffer
PBS, PH7.2.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at 2°C to 8°C upon receipt. Do not freeze.
Dry Ice
No
UniProt ID
P22646
Gene ID
12501
Alias
T3E,TCRE,IMD18,CD3epsilon,T-cell surface glycoprotein CD3 epsilon chain,T-cell surface antigen T3/Leu-4 epsilon chain
Background
Antibody anti-CD3E
Status
RUO

Descripción

CD3E (CD3 epsilon) is one of the key subunits of the T-cell receptor (TCR)-CD3 complex, which is vital for T-cell activation and immune responses. The TCR complex allows T lymphocytes to recognize and respond to antigens presented by major histocompatibility complex (MHC) molecules on antigen-presenting cells (APCs). CD3E plays a critical role in assembling the TCR-CD3 complex and facilitating signal transduction after antigen recognition. The CD3E gene is located on chromosome 11q23 and encodes the CD3ε chain, a type I transmembrane protein essential for the assembly, expression, and signaling function of the TCR. Along with other CD3 subunits (CD3δ, CD3γ, and CD3ζ), CD3E forms part of the signal-transducing complex that transmits signals from the TCR upon antigen engagement. This signal initiates the cascade that leads to T-cell activation, differentiation, and proliferation, all of which are crucial for immune defense against pathogens.

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