CD18 Antibody

Este producto es parte de ITGB2 - integrin subunit beta 2
CD18 Antibody
65€ (25 µg)

Por favor contáctenos para obtener información detallada sobre el precio y disponibilidad.

Name
CD18 Antibody
Category
Primary Antibodies
Provider
Abbexa
Reference
abx229001
Tested Applications
WB, IHC, FCM, IP

Description

CD18 antibody is a Rat monoclonal antibody against CD18.

Documentos del producto

Instrucciones
Data sheet
Descargar

Especificaciones del producto

Category
Primary Antibodies
Immunogen Target
Target: CD18
Host
Rat
Reactivity
Mouse
Clonality
Monoclonal
Conjugation
Unconjugated
Isotype
IgG2a
Size 1
25 µg
Size 2
100 µg
Size 3
1 mg
Tested Applications
WB, IHC, FCM, IP
Buffer
PBS with 0.05% Proclin300.
Availability
Shipped within 5-15 working days.
Storage
Aliquot and store at 2°C to 8°C upon receipt. Do not freeze.
Dry Ice
No
UniProt ID
P11835
Gene ID
16414
Alias
LAD,CD18,MF17,MFI7,LCAMB,LFA-1,MAC-1,Integrin beta-2,Cell surface adhesion glycoproteins LFA-1/CR3/p150,95 subunit beta,Complement receptor C3 subunit beta
Background
Antibody anti-ITGB2
Status
RUO
Note
THIS PRODUCT IS FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC, THERAPEUTIC OR COSMETIC PROCEDURES. NOT FOR HUMAN OR ANIMAL CONSUMPTION.

Background

ITGB2, or integrin subunit beta 2, is a protein that plays a central role in leukocyte adhesion and signaling, facilitating the immune system's response to infections and inflammation. ITGB2, also known as CD18, is part of the integrin family, which consists of transmembrane receptors involved in cell-cell and cell-extracellular matrix (ECM) interactions. Integrins are heterodimeric proteins formed by the association of alpha (α) and beta (β) subunits. In particular, ITGB2 pairs with various alpha integrin subunits to form key receptors known as beta-2 integrins. Beta-2 integrins are primarily expressed on leukocytes (white blood cells) and are essential for mediating cell adhesion, migration, phagocytosis, and immune surveillance. The four major integrins that involve ITGB2 are LFA-1 (αLβ2, CD11a/CD18), Mac-1 (αMβ2, CD11b/CD18), gp150/95 (αXβ2, CD11c/CD18), and αDβ2 (CD11d/CD18). These integrins are vital for the immune system's ability to respond to infections and regulate inflammation.

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