CD157 Antibody (APC)
429€ (100 tests)
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935106861
info@markelab.com
name
CD157 Antibody (APC)
category
Primary Antibodies
provider
Abbexa
reference
abx140199
tested applications
FCM
Description
CD157 Antibody is a Mouse Monoclonal against CD157.
Documents del producto
Instrucciones
Data sheet
Product specifications
| Category | Primary Antibodies |
| Immunogen Target | CD157 |
| Host | Mouse |
| Reactivity | Human, Monkey |
| Recommended Dilution | FCM: 10 µl/100 µl of whole blood or 106 cells. Validated in IHC-F. Optimal dilutions/concentrations should be determined by the end user. |
| Clonality | Monoclonal |
| Conjugation | APC |
| Isotype | IgG1 Kappa |
| Clone ID | T470 |
| Size 1 | 100 tests |
| Tested Applications | FCM |
| Buffer | Stabilizing PBS solution containing 15 mM sodium azide. |
| Availability | Shipped within 5-12 working days. |
| Storage | Store in the dark at 2-8°C. Avoid exposure to light. Do not freeze. |
| Dry Ice | No |
| UniProt ID | Q10588 |
| Gene ID | 683 |
| Alias | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 2,ADP-ribosyl cyclase 2,CD157,Cadpr2,Bone marrow stromal cell antigen 1,Cyclic ADP-ribose hydrolase 2 |
| Background | Antibody anti-BST1 |
| Status | RUO |
Descripción
BST1, also known as bone marrow stromal cell antigen 1 or CD157, is a multifunctional glycoprotein involved in immune signaling, cell adhesion, and calcium signaling. BST1 is part of the ADP-ribosyl cyclase family, which also includes CD38, another NAD-glycohydrolase enzyme involved in immune and calcium signaling. It is encoded by the BST1 gene located on chromosome 4p15 in humans and is predominantly expressed in bone marrow stromal cells, but also in peripheral immune cells, endothelial cells, and various tissues with immune functions. BST1 is also identified as a GPI (glycosylphosphatidylinositol)-anchored protein, which enables it to be tethered to cell membranes, facilitating cell-cell interactions and intracellular signaling. This protein is highly relevant in immunology, given its involvement in cellular processes associated with immune responses and inflammation.
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